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KMID : 0381219830150010019
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Journal of RIMSK
1983 Volume.15 No. 1 p.19 ~ p.27
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Clinical and Immunological Observation of Herpes Zoster
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Abstract
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Herpes zoster is an acute viral infection characterized by vesicular skin lesions which are usually distributed over unilateral sensory dermatomes.
Authors observed 368 cases of herpes zoster clinically for yearly incidence, age, sex, monthly and seasonal distribution, predilection site, associated diseases, complications, and 19 patients immunologically at the Department of Dermatology in Chung-Ang University Hospital during 3 years and 8 months period.
The results were as follows;
1) The incidence of herpes zoster was 2.0% (368cases of total 18, 220 outpatients) and there was a equal sex ratio.
2) As the age increased, the number of patients included in the age group was greater, but total number of herpes zoster was the highest in 20.29 age group.
3) There was no significant monthly or seasonal difference in herpes zoster.
4) The dermatomic involvement of herpes zoster was the most common on thoracic dermatome(57.8%), and others were of trigeminal nerve (10.5%), cervical (9. 57o), lumbar(8.4 7c), sacral (1.9 %) , and multiple dermatomic involvement was 11.7%.
5) Left and right side proporatien of involvement site was about same(196: 171), and bilateral involvement was 1 case.
6) Associated diseases of herpes zoster were observed in 101 patients (´27. 4%) ; hypertension (4.0%), diabetes mellitus(3.8%), tuberculosis (2.4%), post operative status(2.4%), steroid medication (I. 47o), and malignancy (I. 47o).
7) On the development of herpes zoster among 368 patients, three patients had a recent exposure to zoster, and two others had a recent exposure to varicella.
8) The most common complication of herpes zoster was postherpetic neuralgia (7. 370) and others were eye complication (2.2%), scar formation (1.4%), generalized varicelliform eruption (0.8%), motor paralysis (0.5%), superficial gangrene (0.5%), recurrent herpes zoster and RamsayHunt syndrome (0. 3%), respectively.
9) Immunologically, authors observed decreased T cell in herpes zoster patients.
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